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Formation of Cyclophosphamide Specific DNA Adducts in Hematological Diseases

BACKGROUND: Fanconi anemia (FA) patients are hypersensitive to DNA alkylating agents and require lower doses than non-FA patients to minimize serious toxicity. The mechanism by which hypersensitivity occurs is thought to be due to the inability of these individuals to effectively repair drug-induced...

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Sonraí Bibleagrafaíochta
Main Authors: Johnson, L’Aurelle A., Malayappan, Bhaskar, Tretyakova, Natalia, Campbell, Colin, MacMillan, Margaret L., Wagner, John E., Jacobson, Pamala A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204332/
https://ncbi.nlm.nih.gov/pubmed/21793181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.23254
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