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Formation of Cyclophosphamide Specific DNA Adducts in Hematological Diseases
BACKGROUND: Fanconi anemia (FA) patients are hypersensitive to DNA alkylating agents and require lower doses than non-FA patients to minimize serious toxicity. The mechanism by which hypersensitivity occurs is thought to be due to the inability of these individuals to effectively repair drug-induced...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3204332/ https://ncbi.nlm.nih.gov/pubmed/21793181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.23254 |
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