Cellular Repair of DNA–DNA Cross-Links Induced by 1,2,3,4-Diepoxybutane

Xenobiotic-induced interstrand DNA–DNA cross-links (ICL) interfere with transcription and replication and can be converted to toxic DNA double strand breaks. In this work, we investigated cellular responses to 1,4-bis-(guan-7-yl)-2,3-butanediol (bis-N7G-BD) cross-links induced by 1,2,3,4-diepoxybuta...

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Publicado en:Int J Mol Sci
Main Authors: Chesner, Lisa N., Degner, Amanda, Sangaraju, Dewakar, Yomtoubian, Shira, Wickramaratne, Susith, Malayappan, Bhaskar, Tretyakova, Natalia, Campbell, Colin
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454995/
https://ncbi.nlm.nih.gov/pubmed/28524082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18051086
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