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DNA-Protein Cross-Linking by 1,2,3,4-Diepoxybutane
1,2,3,4-Diepoxybutane (DEB) is a strongly genotoxic diepoxide hypothesized to be the ultimate carcinogenic metabolite of the common industrial chemical and environmental carcinogen 1,3-butadiene. DEB is a bis-electrophile capable of cross-linking cellular biomolecules to form DNA-DNA and DNA-protein...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2956319/ https://ncbi.nlm.nih.gov/pubmed/20666492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr1000835 |
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