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High sensitivity of an ELISA kit for detection of the gamma-isoform of 14-3-3 proteins: usefulness in laboratory diagnosis of human prion disease

BACKGROUND: The gamma-isoform of the 14-3-3 protein (14-3-3 gamma) is expressed in neurons, and could be a specific marker for neuronal damage. This protein has been reported as a detectable biomarker, especially in the cerebrospinal fluid (CSF) of Creutzfeldt-Jakob disease (CJD) patients by Western...

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Detalhes bibliográficos
Main Authors: Matsui, Yuki, Satoh, Katsuya, Miyazaki, Toshiaki, Shirabe, Susumu, Atarashi, Ryuichiro, Mutsukura, Kazuo, Satoh, Akira, Kataoka, Yasufumi, Nishida, Noriyuki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204235/
https://ncbi.nlm.nih.gov/pubmed/21970675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2377-11-120
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