High-Resolution 3D Reconstruction Reveals Intra-Synaptic Amyloid Fibrils

β-Amyloid (Aβ) accumulation and aggregation are hallmarks of Alzheimer's disease (AD). High-resolution three-dimensional (HR-3D) volumetric imaging allows for better analysis of fluorescence confocal microscopy and 3D visualization of Aβ pathology in brain. Early intraneuronal Aβ pathology was...

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Autors principals: Capetillo-Zarate, Estibaliz, Gracia, Luis, Yu, Fangmin, Banfelder, Jason R., Lin, Michael T., Tampellini, Davide, Gouras, Gunnar K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2011
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204026/
https://ncbi.nlm.nih.gov/pubmed/21925470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.07.045
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