Rational optimization of reprogramming culture conditions for the generation of induced pluripotent stem cells with ultra-high efficiency and fast kinetics

The ectopic expression of several transcription factors can restore embryonic cell fate to cultured somatic cells and generate induced pluripotent stem cells (iPSCs), revealing a previously unknown pathway to pluripotency. However, this technology is currently limited by low efficiency, slow kinetic...

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Detalhes bibliográficos
Main Authors: Chen, Jiekai, Liu, Jing, Chen, You, Yang, Jiaqi, Chen, Jing, Liu, He, Zhao, Xiangjie, Mo, Kunlun, Song, Hong, Guo, Lin, Chu, Shilong, Wang, Deping, Ding, Ke, Pei, Duanqing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203703/
https://ncbi.nlm.nih.gov/pubmed/21445094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.51
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