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The Sirtuin 2 microtubule deacetylase is an abundant neuronal protein that accumulates in the aging CNS

Sirtuin 2 (SIRT2) is one of seven known mammalian protein deacetylases homologous to the yeast master lifespan regulator Sir2. In recent years, the sirtuin protein deacetylases have emerged as candidate therapeutic targets for many human diseases, including metabolic and age-dependent neurological d...

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Bibliografiske detaljer
Main Authors: Maxwell, Michele M., Tomkinson, Elizabeth M., Nobles, Johnathan, Wizeman, John W., Amore, Allison M., Quinti, Luisa, Chopra, Vanita, Hersch, Steven M., Kazantsev, Aleksey G.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203628/
https://ncbi.nlm.nih.gov/pubmed/21791548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr326
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