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Structural basis for nematode eIF4E binding an m(2,2,7)G-Cap and its implications for translation initiation
Metazoan spliced leader (SL) trans-splicing generates mRNAs with an m(2,2,7)G-cap and a common downstream SL RNA sequence. The mechanism for eIF4E binding an m(2,2,7)G-cap is unknown. Here, we describe the first structure of an eIF4E with an m(2,2,7)G-cap and compare it to the cognate m(7)G-eIF4E co...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3203607/ https://ncbi.nlm.nih.gov/pubmed/21965542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr650 |
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