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Repeat expansion in the budding yeast ribosomal DNA can occur independently of the canonical homologous recombination machinery

Major eukaryotic genomic elements, including the ribosomal DNA (rDNA), are composed of repeated sequences with well-defined copy numbers that must be maintained by regulated recombination. Although mechanisms that instigate rDNA recombination have been identified, none are directional and they there...

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Hlavní autoři: Houseley, Jonathan, Tollervey, David
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203602/
https://ncbi.nlm.nih.gov/pubmed/21768125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr589
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