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Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination
We examined the influence of the tetratricopeptide repeat factor XAB2 on chromosomal break repair, and found that XAB2 promotes end resection that generates the 3′ ssDNA intermediate for homologous recombination (HR). Namely, XAB2 is important for chromosomal double-strand break (DSB) repair via two...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4937314/ https://ncbi.nlm.nih.gov/pubmed/27084940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw275 |
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