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Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination

We examined the influence of the tetratricopeptide repeat factor XAB2 on chromosomal break repair, and found that XAB2 promotes end resection that generates the 3′ ssDNA intermediate for homologous recombination (HR). Namely, XAB2 is important for chromosomal double-strand break (DSB) repair via two...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Onyango, David O., Howard, Sean M., Neherin, Kashfia, Yanez, Diana A., Stark, Jeremy M.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937314/
https://ncbi.nlm.nih.gov/pubmed/27084940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw275
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