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Local sensing of global DNA topology: from crossover geometry to type II topoisomerase processivity

Type II topoisomerases are ubiquitous enzymes that control the topology and higher order structures of DNA. Type IIA enzymes have the remarkable property to sense locally the global DNA topology. Although many theoretical models have been proposed, the molecular mechanism of chiral discrimination is...

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Bibliografski detalji
Glavni autor: Timsit, Youri
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203592/
https://ncbi.nlm.nih.gov/pubmed/21764774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr556
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