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Inferring Global Topology from Local Juxtaposition Geometry: Interlinking Polymer Rings and Ramifications for Topoisomerase Action

Lattice modeling is applied to investigate how the configurations of local chain juxtapositions may provide information about whether two ring polymers (loops) are topologically linked globally. Given a particular juxtaposition, the conditional probability that the loops are linked is determined by...

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Detalhes bibliográficos
Main Authors: Liu, Zhirong, Zechiedrich, E. Lynn, Chan, Hue Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1403174/
https://ncbi.nlm.nih.gov/pubmed/16537549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.076778
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