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Local site preference rationalizes disentangling by DNA topoisomerases

To rationalize the disentangling action of type II topoisomerases, an improved wormlike DNA model was used to delineate the degree of unknotting and decatenating achievable by selective segment passage at specific juxtaposition geometries and to determine how these activities were affected by DNA ci...

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Dettagli Bibliografici
Autori principali: Liu, Zhirong, Zechiedrich, Lynn, Chan, Hue Sun
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645352/
https://ncbi.nlm.nih.gov/pubmed/20365765
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