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Topoisomerase IB-DNA Interactions: X Marks the Spot
The observation made twenty years ago that type IB topoisomerases bound DNA helix-helix juxtapositions was unexpected, given the controlled helical rotation mechanism of the enzyme. In this issue, Patel et al. (2010) provide an elegant structural explanation for this interaction.
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891060/ https://ncbi.nlm.nih.gov/pubmed/20541502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.05.002 |
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