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Electrostatics of DNA–DNA juxtapositions: consequences for type II topoisomerase function

Type II topoisomerases resolve problematic DNA topologies such as knots, catenanes, and supercoils that arise as a consequence of DNA replication and recombination. Failure to remove problematic DNA topologies prohibits cell division and can result in cell death or genetic mutation. Such catastrophi...

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Autors principals: Randall, Graham L, Pettitt, B Montgomery, Buck, Gregory R, Zechiedrich, E Lynn
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603137/
https://ncbi.nlm.nih.gov/pubmed/19088861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/0953-8984/18/14/S03
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