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Electrostatics of DNA–DNA juxtapositions: consequences for type II topoisomerase function
Type II topoisomerases resolve problematic DNA topologies such as knots, catenanes, and supercoils that arise as a consequence of DNA replication and recombination. Failure to remove problematic DNA topologies prohibits cell division and can result in cell death or genetic mutation. Such catastrophi...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2603137/ https://ncbi.nlm.nih.gov/pubmed/19088861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/0953-8984/18/14/S03 |
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