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Quality control in the initiation of eukaryotic DNA replication

Origins of DNA replication must be regulated to ensure that the entire genome is replicated precisely once in each cell cycle. In human cells, this requires that tens of thousands of replication origins are activated exactly once per cell cycle. Failure to do so can lead to cell death or genome rear...

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Dettagli Bibliografici
Autore principale: Diffley, John F. X.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203456/
https://ncbi.nlm.nih.gov/pubmed/22084381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2011.0073
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