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Pyomelanin Formation in Aspergillus fumigatus Requires HmgX and the Transcriptional Activator HmgR but Is Dispensable for Virulence
The opportunistic human pathogenic fungus Aspergillus fumigatus is able to produce the dark brown pigment pyomelanin by degradation of L-tyrosine. Pyomelanin was shown to protect the fungus against reactive oxygen intermediates as well as cell wall disturbing compounds and is therefore assumed to pr...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3203155/ https://ncbi.nlm.nih.gov/pubmed/22046314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026604 |
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