Human and Plant Fungal Pathogens: The Role of Secondary Metabolites

Por Scharf, Daniel H., Heinekamp, Thorsten, Brakhage, Axel A.
Publicado em 2014

Heptahelical Receptors GprC and GprD of Aspergillus fumigatus Are Essential Regulators of Colony Growth, Hyphal Morphogenesis, and Virulence

Por Gehrke, Alexander, Heinekamp, Thorsten, Jacobsen, Ilse D., Brakhage, Axel A.
Publicado em 2010

Protein Kinase A Regulates Growth, Sporulation, and Pigment Formation in Aspergillus fumigatus

Por Grosse, Christina, Heinekamp, Thorsten, Kniemeyer, Olaf, Gehrke, Alexander, Brakhage, Axel A.
Publicado em 2008

Heavy Metal-Induced Expression of PcaA Provides Cadmium Tolerance to Aspergillus fumigatus and Supports Its Virulence in the Galleria mellonella Model

Por Bakti, Fruzsina, Sasse, Christoph, Heinekamp, Thorsten, Pócsi, István, Braus, Gerhard H.
Publicado no Front Microbiol (2018)

Systems Biology of Fungal Infection

Por Horn, Fabian, Heinekamp, Thorsten, Kniemeyer, Olaf, Pollmächer, Johannes, Valiante, Vito, Brakhage, Axel A.
Publicado em 2012

Aspergillus fumigatus melanins: interference with the host endocytosis pathway and impact on virulence

Por Heinekamp, Thorsten, Thywißen, Andreas, Macheleidt, Juliane, Keller, Sophia, Valiante, Vito, Brakhage, Axel A.
Publicado em 2013

Characterization of the Aspergillus fumigatus detoxification systems for reactive nitrogen intermediates and their impact on virulence

Por Lapp, Katrin, Vödisch, Martin, Kroll, Kristin, Strassburger, Maria, Kniemeyer, Olaf, Heinekamp, Thorsten, Brakhage, Axel A.
Publicado em 2014

Production of Pyomelanin, a Second Type of Melanin, via the Tyrosine Degradation Pathway in Aspergillus fumigatus

Por Schmaler-Ripcke, Jeannette, Sugareva, Venelina, Gebhardt, Peter, Winkler, Robert, Kniemeyer, Olaf, Heinekamp, Thorsten, Brakhage, Axel A.
Publicado em 2009

Pyomelanin Formation in Aspergillus fumigatus Requires HmgX and the Transcriptional Activator HmgR but Is Dispensable for Virulence

Por Keller, Sophia, Macheleidt, Juliane, Scherlach, Kirstin, Schmaler-Ripcke, Jeannette, Jacobsen, Ilse D., Heinekamp, Thorsten, Brakhage, Axel A.
Publicado em 2011

Genetic Engineering Activates Biosynthesis of Aromatic Fumaric Acid Amides in the Human Pathogen Aspergillus fumigatus

Por Kalb, Daniel, Heinekamp, Thorsten, Lackner, Gerald, Scharf, Daniel H., Dahse, Hans-Martin, Brakhage, Axel A., Hoffmeister, Dirk
Publicado no Appl Environ Microbiol (2015)

Conidial Dihydroxynaphthalene Melanin of the Human Pathogenic Fungus Aspergillus fumigatus Interferes with the Host Endocytosis Pathway

Por Thywißen, Andreas, Heinekamp, Thorsten, Dahse, Hans-Martin, Schmaler-Ripcke, Jeannette, Nietzsche, Sandor, Zipfel, Peter F., Brakhage, Axel A.
Publicado em 2011

N‐Heterocyclization in Gliotoxin Biosynthesis is Catalyzed by a Distinct Cytochrome P450 Monooxygenase

Por Scharf, Daniel H., Chankhamjon, Pranatchareeya, Scherlach, Kirstin, Dworschak, Jan, Heinekamp, Thorsten, Roth, Martin, Brakhage, Axel A., Hertweck, Christian
Publicado no Chembiochem (2020)

The MAP kinase MpkA controls cell wall integrity, oxidative stress response, gliotoxin production and iron adaptation in Aspergillus fumigatus

Por Jain, Radhika, Valiante, Vito, Remme, Nicole, Docimo, Teresa, Heinekamp, Thorsten, Hertweck, Christian, Gershenzon, Jonathan, Haas, Hubertus, Brakhage, Axel A
Publicado em 2011

Interference of Aspergillus fumigatus with the immune response

Por Heinekamp, Thorsten, Schmidt, Hella, Lapp, Katrin, Pähtz, Vera, Shopova, Iordana, Köster-Eiserfunke, Nora, Krüger, Thomas, Kniemeyer, Olaf, Brakhage, Axel A.
Publicado no Semin Immunopathol (2014)

The Pheromone Module SteC-MkkB-MpkB-SteD-HamE Regulates Development, Stress Responses and Secondary Metabolism in Aspergillus fumigatus

Por Frawley, Dean, Stroe, Maria C., Oakley, Berl R., Heinekamp, Thorsten, Straßburger, Maria, Fleming, Alastair B., Brakhage, Axel A., Bayram, Özgür
Publicado no Front Microbiol (2020)

Activity and Safety of Inhaled Itraconazole Nanosuspension in a Model Pulmonary Aspergillus fumigatus Infection in Inoculated Young Quails

Por Wlaź, Piotr, Knaga, Sebastian, Kasperek, Kornel, Wlaź, Aleksandra, Poleszak, Ewa, Jeżewska-Witkowska, Grażyna, Winiarczyk, Stanisław, Wyska, Elżbieta, Heinekamp, Thorsten, Rundfeldt, Chris
Publicado no Mycopathologia (2015)

Proteomics of Aspergillus fumigatus Conidia-containing Phagolysosomes Identifies Processes Governing Immune Evasion

Por Schmidt, Hella, Vlaic, Sebastian, Krüger, Thomas, Schmidt, Franziska, Balkenhol, Johannes, Dandekar, Thomas, Guthke, Reinhard, Kniemeyer, Olaf, Heinekamp, Thorsten, Brakhage, Axel A.
Publicado no Mol Cell Proteomics (2018)

The Crystal Structure of Peroxiredoxin Asp f3 Provides Mechanistic Insight into Oxidative Stress Resistance and Virulence of Aspergillus fumigatus

Por Hillmann, Falk, Bagramyan, Karine, Straßburger, Maria, Heinekamp, Thorsten, Hong, Teresa B., Bzymek, Krzysztof P., Williams, John C., Brakhage, Axel A., Kalkum, Markus
Publicado no Sci Rep (2016)

SCF Ubiquitin Ligase F-box Protein Fbx15 Controls Nuclear Co-repressor Localization, Stress Response and Virulence of the Human Pathogen Aspergillus fumigatus

Por Jöhnk, Bastian, Bayram, Özgür, Abelmann, Anja, Heinekamp, Thorsten, Mattern, Derek J., Brakhage, Axel A., Jacobsen, Ilse D., Valerius, Oliver, Braus, Gerhard H.
Publicado no PLoS Pathog (2016)

Direct Visualization of Fungal Burden in Filamentous Fungus-Infected Silkworms

Por Yu, Yidong, Wolf, Ann-Katrin, Thusek, Sina, Heinekamp, Thorsten, Bromley, Michael, Krappmann, Sven, Terpitz, Ulrich, Voigt, Kerstin, Brakhage, Axel A., Beilhack, Andreas
Publicado no J Fungi (Basel) (2021)