Production of Pyomelanin, a Second Type of Melanin, via the Tyrosine Degradation Pathway in Aspergillus fumigatus

Aspergillus fumigatus is the most important airborne fungal pathogen of immunosuppressed humans. A. fumigatus is able to produce dihydroxynaphthalene melanin, which is predominantly present in the conidia. Its biosynthesis is an important virulence determinant. Here, we show that A. fumigatus is abl...

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Hauptverfasser: Schmaler-Ripcke, Jeannette, Sugareva, Venelina, Gebhardt, Peter, Winkler, Robert, Kniemeyer, Olaf, Heinekamp, Thorsten, Brakhage, Axel A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
Schlagworte:
Mycology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2620705/
https://ncbi.nlm.nih.gov/pubmed/19028908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02077-08
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