Production of Pyomelanin, a Second Type of Melanin, via the Tyrosine Degradation Pathway in Aspergillus fumigatus

Aspergillus fumigatus is the most important airborne fungal pathogen of immunosuppressed humans. A. fumigatus is able to produce dihydroxynaphthalene melanin, which is predominantly present in the conidia. Its biosynthesis is an important virulence determinant. Here, we show that A. fumigatus is abl...

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Detalhes bibliográficos
Main Authors: Schmaler-Ripcke, Jeannette, Sugareva, Venelina, Gebhardt, Peter, Winkler, Robert, Kniemeyer, Olaf, Heinekamp, Thorsten, Brakhage, Axel A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Mycology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2620705/
https://ncbi.nlm.nih.gov/pubmed/19028908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02077-08
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