Coupled pre-mRNA and mRNA dynamics unveil operational strategies underlying transcriptional responses to stimuli

Transcriptional responses to extracellular stimuli involve tuning the rates of transcript production and degradation. Here, we show that the time-dependent profiles of these rates can be inferred from simultaneous measurements of precursor mRNA (pre-mRNA) and mature mRNA profiles. Transcriptome-wide...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Zeisel, Amit, Köstler, Wolfgang J, Molotski, Natali, Tsai, Jonathan M, Krauthgamer, Rita, Jacob-Hirsch, Jasmine, Rechavi, Gideon, Soen, Yoav, Jung, Steffen, Yarden, Yosef, Domany, Eytan
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2011
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202801/
https://ncbi.nlm.nih.gov/pubmed/21915116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.62
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