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Copper Transporters and the Cellular Pharmacology of the Platinum-Containing Cancer Drugs

Multiple lines of evidence indicate that the platinum-containing cancer drugs enter cells, are distributed to various subcellular compartments, and are exported from cells via transporters that evolved to manage copper homeostasis. The cytotoxicity of the platinum drugs is directly related to how mu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Howell, Stephen B., Safaei, Roohangiz, Larson, Christopher A., Sailor, Michael J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Pharmacology and Experimental Therapeutics 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202487/
https://ncbi.nlm.nih.gov/pubmed/20159940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.063172
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