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The Role of the Mammalian Copper Transporter 1 in the Cellular Accumulation of Platinum-Based Drugs
The mammalian copper transporter 1 (CTR1) is responsible for the uptake of copper from the extracellular space. In this study, we used an isogenic pair of CTR1(+/+) and CTR1(-/-) mouse embryo fibroblasts to examine the contribution of CTR1 to the influx of cisplatin (DDP), carboplatin (CBDCA), oxali...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Pharmacology and Experimental Therapeutics
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2684896/ https://ncbi.nlm.nih.gov/pubmed/18996970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.052381 |
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