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The Role of the N-terminus of Mammalian Copper Transporter 1 in the Cellular Accumulation of Cisplatin
The mammalian Copper Transporter 1 (CTR1) is responsible for the uptake of copper (Cu) from the extracellular space, and has been shown to play a major role in the initial accumulation of platinum-based drugs. In this study we re-expressed wild type and structural variants of hCTR1 in mouse embryo f...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2900501/ https://ncbi.nlm.nih.gov/pubmed/20451502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2010.04.030 |
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