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The Role of the N-terminus of Mammalian Copper Transporter 1 in the Cellular Accumulation of Cisplatin

The mammalian Copper Transporter 1 (CTR1) is responsible for the uptake of copper (Cu) from the extracellular space, and has been shown to play a major role in the initial accumulation of platinum-based drugs. In this study we re-expressed wild type and structural variants of hCTR1 in mouse embryo f...

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Bibliografiska uppgifter
Huvudupphovsmän: Larson, Christopher A., Adams, Preston L., Jandial, Danielle D., Blair, Brian G., Safaei, Roohangiz, Howell, Stephen B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900501/
https://ncbi.nlm.nih.gov/pubmed/20451502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2010.04.030
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