Urinary levels of the tobacco-specific carcinogen N′-nitrosonornicotine and its glucuronide are strongly associated with esophageal cancer risk in smokers

N′-Nitrosonornicotine (NNN) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) are tobacco-specific nitrosamines. NNN and NNK can induce cancers of the esophagus and lung, respectively, in laboratory animals, but data on human esophageal cancer are lacking. The association between levels of NN...

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Detalles Bibliográficos
Main Authors: Yuan, Jian-Min, Knezevich, Aleksandar D., Wang, Renwei, Gao, Yu-Tang, Hecht, Stephen S., Stepanov, Irina
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2011
Assuntos:
Molecular Epidemiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202311/
https://ncbi.nlm.nih.gov/pubmed/21734256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr125
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