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The Ratio of a Urinary Tobacco-Specific Lung Carcinogen Metabolite to Cotinine is Significantly Higher in Passive than in Active Smokers

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol plus its glucuronides (total NNAL), metabolites of the lung carcinogen NNK, and total cotinine, metabolites of nicotine, are biomarkers of active and passive cigarette smoking. We calculated the total NNAL: total cotinine (× 10(3)) ratio in 408 passive (...

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Autori principali: Vogel, Rachel Isaksson, Carmella, Steven G., Stepanov, Irina, Hatsukami, Dorothy K., Hecht, Stephen S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159775/
https://ncbi.nlm.nih.gov/pubmed/21812592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/1354750X.2011.598565
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