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Nornicotine Nitrosation in Saliva and Its Relation to Endogenous Synthesis of N′-Nitrosonornicotine in Humans

INTRODUCTION: We recently reported that certain amounts of the carcinogen N′-nitrosonornicotine (NNN) can be formed endogenously from nicotine and/or nornicotine in some users of oral nicotine replacement therapy products. Although the acidic environment of the stomach creates the most favorable con...

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Detalhes bibliográficos
Main Authors: Knezevich, Aleksandar, Muzic, John, Hatsukami, Dorothy K., Hecht, Stephen S., Stepanov, Irina
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3611998/
https://ncbi.nlm.nih.gov/pubmed/22923602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ntr/nts172
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