DNMT3A Mutations in Acute Myeloid Leukemia

BACKGROUND: The genetic alterations responsible for an adverse outcome in most patients with acute myeloid leukemia (AML) are unknown. METHODS: Using massively parallel DNA sequencing, we identified a somatic mutation in DNMT3A, encoding a DNA methyltransferase, in the genome of cells from a patient...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Ley, Timothy J., Ding, Li, Walter, Matthew J., McLellan, Michael D., Lamprecht, Tamara, Larson, David E., Kandoth, Cyriac, Payton, Jacqueline E., Baty, Jack, Welch, John, Harris, Christopher C., Lichti, Cheryl F., Townsend, R. Reid, Fulton, Robert S., Dooling, David J., Koboldt, Daniel C., Schmidt, Heather, Zhang, Qunyuan, Osborne, John R., Lin, Ling, O’Laughlin, Michelle, McMichael, Joshua F., Delehaunty, Kim D., McGrath, Sean D., Fulton, Lucinda A., Magrini, Vincent J., Vickery, Tammi L., Hundal, Jasreet, Cook, Lisa L., Conyers, Joshua J., Swift, Gary W., Reed, Jerry P., Alldredge, Patricia A., Wylie, Todd, Walker, Jason, Kalicki, Joelle, Watson, Mark A., Heath, Sharon, Shannon, William D., Varghese, Nobish, Nagarajan, Rakesh, Westervelt, Peter, Tomasson, Michael H., Link, Daniel C., Graubert, Timothy A., DiPersio, John F., Mardis, Elaine R., Wilson, Richard K.
格式: Artigo
語言:Inglês
出版: 2010
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201818/
https://ncbi.nlm.nih.gov/pubmed/21067377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1005143
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍