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The origin and evolution of mutations in Acute Myeloid Leukemia
Most mutations in cancer genomes are thought to be acquired after the initiating event, which may cause genomic instability, driving clonal evolution. However, for acute myeloid leukemia (AML), normal karyotypes are common, and genomic instability is unusual. To better understand clonal evolution in...
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3407563/ https://ncbi.nlm.nih.gov/pubmed/22817890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.06.023 |
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