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The kinetics of phosphotriester condensation reactions on solid support.

A study has been made of the kinetics of condensation reactions in phosphotriester synthesis of oligonucleotides on polystyrene copolymer resin support, using monomers, dimers, and trimers as the coupling units. The condensations follow pseudo first order kinetics, with a rate constant that decrease...

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Detalles Bibliográficos
Main Authors: Ikuta, S, Chattopadhyaya, R, Dickerson, R E
Formato: Artigo
Idioma:Inglês
Publicado: 1984
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC320092/
https://ncbi.nlm.nih.gov/pubmed/6473109
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