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Development of a diphtheria toxin based anti-porcine CD3 recombinant immunotoxin
Anti-CD3 immunotoxins, which induce profound but transient T cell depletion in vivo by inhibiting eukaryotic protein synthesis in CD3+ cells, are effective reagents in large animal models of transplantation tolerance and autoimmune disease therapy. A diphtheria toxin based anti-porcine CD3 recombina...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3200572/ https://ncbi.nlm.nih.gov/pubmed/21866954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200230h |
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