Effect of pre-existing anti-diphtheria toxin antibodies on T cell depletion levels following diphtheria toxin-based recombinant anti-monkey CD3 immunotoxin treatment

Diphtheria toxin (DT)-based anti-CD3 immunotoxins have clinical relevance in numerous applications including autoimmune disease therapies and organ transplantation tolerance protocols. Pre-existing anti-DT antibodies acquired either by vaccination against diphtheria toxin or infections with C. dipht...

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Main Authors: Matar, Abraham J., Pathiraja, Vimukthi, Wang, Zhirui, Duran-Struuck, Raimon, Gusha, Ashley, Crepeau, Rebecca, Tasaki, Masayuki, Sachs, David H., Huang, Christene A.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413771/
https://ncbi.nlm.nih.gov/pubmed/22676970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trim.2012.05.003
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