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A Gold Nanoparticle Based Approach for Screening Triplex DNA Binders

Nanoparticle assemblies interconnected with DNA triple helixes can be used to colorimetrically screen for triplex DNA binding molecules and simultaneously determine their relative binding affinities based on melting temperatures. Nanoparticles assemble only when DNA triple helixes form between DNA f...

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Autors principals: Han, Min Su, Lytton-Jean, Abigail K. R., Mirkin, Chad A.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3200552/
https://ncbi.nlm.nih.gov/pubmed/16608320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0606475
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