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A Gold Nanoparticle Based Approach for Screening Triplex DNA Binders
Nanoparticle assemblies interconnected with DNA triple helixes can be used to colorimetrically screen for triplex DNA binding molecules and simultaneously determine their relative binding affinities based on melting temperatures. Nanoparticles assemble only when DNA triple helixes form between DNA f...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3200552/ https://ncbi.nlm.nih.gov/pubmed/16608320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0606475 |
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