Phosphorylation: The Molecular Switch of Double-Strand Break Repair

Repair of double-stranded breaks (DSBs) is vital to maintaining genomic stability. In mammalian cells, DSBs are resolved in one of the following complex repair pathways: nonhomologous end-joining (NHEJ), homologous recombination (HR), or the inclusive DNA damage response (DDR). These repair pathways...

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Detalhes bibliográficos
Main Authors: Summers, K. C., Shen, F., Sierra Potchanant, E. A., Phipps, E. A., Hickey, R. J., Malkas, L. H.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3200257/
https://ncbi.nlm.nih.gov/pubmed/22084686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/373816
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