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Signaling Proteins and Transcription Factors in Normal and Malignant Early B Cell Development

B cell development starts in bone marrow with the commitment of hematopoietic progenitors to the B cell lineage. In murine models, the IL-7 and preBCR receptors, and the signaling pathways and transcription factors that they regulate, control commitment and maintenance along the B cell pathway. E2A,...

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Detalhes bibliográficos
Main Authors: Pérez-Vera, Patricia, Reyes-León, Adriana, Fuentes-Pananá, Ezequiel M.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3200079/
https://ncbi.nlm.nih.gov/pubmed/22046564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/502751
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