Cell Fate Decisions: The Role of Transcription Factors in Early B-cell Development and Leukemia

B cells are an integral part of the adaptive immune system and regulate innate immunity. Derived from hematopoietic stem cells, B cells mature through a series of cell fate decisions. Complex transcriptional circuits form and dissipate dynamically during these lineage restrictions. Genomic aberratio...

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Bibliografiske detaljer
Udgivet i:Blood Cancer Discov
Main Authors: Fischer, Ute, Yang, Jun J., Ikawa, Tomokatsu, Hein, Daniel, Vicente-Dueñas, Carolina, Borkhardt, Arndt, Sánchez-García, Isidro
Format: Artigo
Sprog:Inglês
Udgivet: American Association for Cancer Research 2020
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7774874/
https://ncbi.nlm.nih.gov/pubmed/33392513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2643-3230.BCD-20-0011
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