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p53-independent Epigenetic Repression of the p21(WAF1) Gene in T-cell Acute Lymphoblastic Leukemia
The p53 protein is a primary mediator of cellular apoptosis and growth arrest after exposure to DNA-damaging agents. Previous work has shown that the majority of childhood acute lymphoblastic leukemia (ALL) cases express a wild type p53 gene, although the functionality of the p53 pathway has rarely...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Biochemistry and Molecular Biology
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3199508/ https://ncbi.nlm.nih.gov/pubmed/21903579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.272336 |
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