p21(WAF1) modulates drug-induced apoptosis and cell cycle arrest in B-cell precursor acute lymphoblastic leukemia

p21(WAF1) is a well-characterized mediator of cell cycle arrest and may also modulate chemotherapy-induced cell death. The role of p21(WAF1) in drug-induced cell cycle arrest and apoptosis of acute lymphoblastic leukemia (ALL) cells was investigated using p53-functional patient-derived xenografts (P...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Davies, Carwyn, Hogarth, Linda A, Mackenzie, Karen L, Hall, Andrew G, Lock, Richard B
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825786/
https://ncbi.nlm.nih.gov/pubmed/26506264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1100774
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