Chemokine CXCL12 Uses CXCR4 and a Signaling Core Formed by Bifunctional Akt, Extracellular Signal-regulated Kinase (ERK)1/2, and Mammalian Target of Rapamycin Complex 1 (mTORC1) Proteins to Control Chemotaxis and Survival Simultaneously in Mature Dendritic Cells

Chemokines control several cell functions in addition to chemotaxis. Although much information is available on the involvement of specific signaling molecules in the control of single functions controlled by chemokines, especially chemotaxis, the mechanisms used by these ligands to regulate several...

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Detalles Bibliográficos
Autores principales: Delgado-Martín, Cristina, Escribano, Cristina, Pablos, José Luis, Riol-Blanco, Lorena, Rodríguez-Fernández, José Luis
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199470/
https://ncbi.nlm.nih.gov/pubmed/21878648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.294116
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