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Differential and Complementary Effects of Glucose and Prolactin on Islet DNA Synthesis and Gene Expression
The mechanisms by which lactogenic hormones promote β-cell expansion remain poorly understood. Because prolactin (PRL) up-regulates β-cell glucose transporter 2, glucokinase, and pyruvate dehydrogenase activities, we reasoned that glucose availability might mediate or modulate the effects of PRL on...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Endocrine Society
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3198965/ https://ncbi.nlm.nih.gov/pubmed/21239441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-1258 |
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