Regulation of Islet β-Cell Pyruvate Metabolism: Interactions of Prolactin, Glucose, and Dexamethasone

Prolactin (PRL) induces β-cell proliferation and glucose-stimulated insulin secretion (GSIS) and counteracts the effects of glucocorticoids on insulin production. The mechanisms by which PRL up-regulates GSIS are unknown. We used rat islets and insulinoma (INS-1) cells to explore the interactions of...

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Main Authors: Arumugam, Ramamani, Horowitz, Eric, Noland, Robert C., Lu, Danhong, Fleenor, Donald, Freemark, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903933/
https://ncbi.nlm.nih.gov/pubmed/20484462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0049
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