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Regulation of Islet β-Cell Pyruvate Metabolism: Interactions of Prolactin, Glucose, and Dexamethasone
Prolactin (PRL) induces β-cell proliferation and glucose-stimulated insulin secretion (GSIS) and counteracts the effects of glucocorticoids on insulin production. The mechanisms by which PRL up-regulates GSIS are unknown. We used rat islets and insulinoma (INS-1) cells to explore the interactions of...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Endocrine Society
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903933/ https://ncbi.nlm.nih.gov/pubmed/20484462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0049 |
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