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Probing Single-Molecule Enzyme Active-Site Conformational State Intermittent Coherence

The relationship between protein conformational dynamics and enzymatic reactions has been a fundamental focus in modern enzymology. Using single-molecule Fluorescence Resonance Energy Transfer (FRET) with a combined statistical data analysis approach, we have identified the intermittently appearing...

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Detalhes bibliográficos
Main Authors: He, Yufan, Li, Yue, Mukherjee, Saptarshi, Wu, Yan, Yan, Honggao, Lu, H. Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198842/
https://ncbi.nlm.nih.gov/pubmed/21823644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja204644y
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