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Interrogating the activities of conformational deformed enzyme by single-molecule fluorescence-magnetic tweezers microscopy
Characterizing the impact of fluctuating enzyme conformation on enzymatic activity is critical in understanding the structure–function relationship and enzymatic reaction dynamics. Different from studying enzyme conformations under a denaturing condition, it is highly informative to manipulate the c...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4653173/ https://ncbi.nlm.nih.gov/pubmed/26512103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1506405112 |
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