Rational Truncation of an RNA Aptamer to Prostate-Specific Membrane Antigen Using Computational Structural Modeling

RNA aptamers represent an emerging class of pharmaceuticals with great potential for targeted cancer diagnostics and therapy. Several RNA aptamers that bind cancer cell-surface antigens with high affinity and specificity have been described. However, their clinical potential has yet to be realized....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rockey, William M., Hernandez, Frank J., Huang, Sheng-You, Cao, Song, Howell, Craig A., Thomas, Gregory S., Liu, Xiu Ying, Lapteva, Natalia, Spencer, David M., McNamara, James O., Zou, Xiaoqin, Chen, Shi-Jie, Giangrande, Paloma H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc. 2011
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198747/
https://ncbi.nlm.nih.gov/pubmed/22004414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2011.0313
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