Structural basis of prostate-specific membrane antigen recognition by the A9g RNA aptamer

Prostate-specific membrane antigen (PSMA) is a well-characterized tumor marker associated with prostate cancer and neovasculature of most solid tumors. PSMA-specific ligands are thus being developed to deliver imaging or therapeutic agents to cancer cells. Here, we report on a crystal structure of h...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Ptacek, Jakub, Zhang, Dong, Qiu, Liming, Kruspe, Sven, Motlova, Lucia, Kolenko, Petr, Novakova, Zora, Shubham, Shambhavi, Havlinova, Barbora, Baranova, Petra, Chen, Shi-Jie, Zou, Xiaoqin, Giangrande, Paloma, Barinka, Cyril
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Structural Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641732/
https://ncbi.nlm.nih.gov/pubmed/32525981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa494
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