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The PDE4 inhibitor rolipram prevents NF-kappaB binding activity and proinflammatory cytokine release in human chorionic cells

Spontaneous preterm delivery is linked to intrauterine inflammation. Fetal membranes are involved in the inflammatory process as an important source of mediators, and the chorion leave produces high levels of the pro-inflammatory cytokine TNFα when stimulated by LPS. The transcription factor NF-κB i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hervé, Roxane, Schmitz, Thomas, Evain-Brion, Danièle, Cabrol, Dominique, Leroy, Marie-Josèphe, Méhats, Céline
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Association of Immunologists 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198604/
https://ncbi.nlm.nih.gov/pubmed/18641359
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