Effects of ketamine on proinflammatory cytokines and nuclear factor kappaB in polymicrobial sepsis rats

AIM: To explore the effects of ketamine on hemo-dynamics, plasma proinflammatory cytokine (TNF-α and IL-6) levels and nuclear factor kappa B (NF-κB) activation during polymicrobial sepsis. METHODS: Male Sprague-Dawlay rats were subjected to cecal ligation and puncture (CLP) or sham operation. The ra...

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Autores principales: Song, Xue-Min, Li, Jian-Guo, Wang, Yan-Lin, Zhou, Qing, Du, Zhao-Hui, Jia, Bao-Hui, Ke, Jian-Juan
Formato: Artigo
Lenguaje:Inglês
Publicado: Baishideng Publishing Group Co., Limited 2006
Materias:
Rapid Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4087497/
https://ncbi.nlm.nih.gov/pubmed/17143955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i45.7350
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